Courses

2017-2018 LMP Course Offerings

OVERVIEW

To graduate with an LMP Specialist under your belt, you will need these courses in the following years.

1st Year: (BIO120H1, BIO130H1); (CHM138H1, CHM139H1)/CHM151Y1; (MAT135H1, MAT136H1)/MAT137Y1/MAT157Y1; (PHY131H1, PHY132H1)/(PHY151H1, PHY152H1)

2nd Year: BCH210H1; BIO230H1; BIO260H1/HMB265H1; CHM220H1; CHM247H1/CHM249H1; PSL300H1; PSL301H1; STA220H1/BIO220H1

3rd Year: BCH370H1; BCH311H1/CSB349H1; (IMM340H1, IMM350H1)/(IMM341H1, IMM351H1)/(MGY377H1, MGY378H1); LMP300Y1; LMP365H1

4th Year: At least 4 of LMP402H1, LMP403H1, LMP405Y1, LMP406H1, LMP408H1, LMP410H1, LMP415H1, LMP436H1.  (Note: If the research project LMP405Y1 is taken, three additional courses from the list are still required.)

 

LIST OF COURSES

LMP300Y1:    Introduction to Pathobiology
Concepts in pathogenesis; cell injury and death; tissue structure, wound healing; repair and fibrosis. Molecular basis of major organ system pathology. The laboratory examines gross anatomical specimens and introduces histopathology. Enrolment is limited to students specializing in pathobiology who have completed the first and second year requirements of the program.

Exclusion: LMP301H1, LMP363H1
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP301H1:    Introduction to the Biochemistry of Human Disease
Introduces concepts and mechanisms of disease processes as they arise from disturbances of normal biochemical and physiological functions. The rational use of the clinical biochemistry laboratory in the diagnosis and management of disease is explained. Not intended for students in the Pathobiology Specialist program.

Prerequisite: BCH210H1/BCH242Y1
Exclusion: LMP300Y1
Recommended Preparation: PSL201Y1/300H1/301H1
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP363H1:    Principles of Pathobiology
Pathological changes brought on by foreign compounds; applications of pathology to the detection of toxic carcinogenic actions.

Prerequisite: BIO230H1, CHM247H1/CHM249H1, *Permission from the department for non-specialists*
Exclusion: LMP300Y1
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP365H1:    Neoplasia
A general introduction to the cellular and molecular aspects of cancer and its etiology. The laboratory component presents the range of benign and malignant tumor types at the gross and histological levels. Pathophysiology of cancer, invasion and metastases, role of the immune system.

Corequisite: LMP300Y1 or permission of department
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP402H1:    Inflammation and Infection
Mechanisms that allow microbial pathogens to cause disease and the host to detect infection, mount an inflammatory response and resolve the infection.  Primary research articles are discussed.  Topics include commensal bacteria, bacterial toxins, pattern recognition receptors, leukocyte emigration, chemotaxis, and the role of non-coding RNAs in immunity.

Prerequisite: (IMM340H1, IMM35oH1)/(IMM341H1, IMM351H1)/(MGY377H1, MGY378H1)
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP403H1:    Immunopathology
The immune system in disease. Responses of the immune system to host invasion, injurious stimuli, and transplantation. Immunopathology of organ-specific diseases including pancreas, gut, liver, heart, kidney, and blood. Intended for students specializing in pathobiology or related programs.

Prerequisite: (IMM340H1, IMM350H1)/(IMM341H1, IMM351H1)
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP405Y1:    Project in Pathobiology
A self-contained research project to be completed under the supervision of a faculty member. The main areas of research are as listed in the description of the Department (above). The student will normally have completed three full years of study, and is expected to devote at least one full day per week to the project. Admission is by arrangement with the Department and with a particular supervisor. A list of potential supervisors is available from the Departmental Office and on our web site.

Prerequisite: BCH210H1/BCH242Y1, LMP300Y1/LMP363H1/LMP365H1 and permission of department
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP406H1:    Pathobiology of the Cardiovascular System
Pathobiology of the heart, blood vessels, and lymphatic system. Congenital diseases of the heart, ischemic injury, stroke. Treatments of vascular disease and cardiovascular biomaterials. Major focus on atherosclerosis and hypertension. The emphasis is on the underlying cell biology of these processes.

Prerequisite: (PSL300H1, PSL301H1)/PSL302Y1
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP408H1:    Pathobiology of Neurodegenerative Disease

Introduces use of genetic model systems and organisms in exploring aspects of human reproduction, development, and disease. A major focus is on the impact of the genetic models on understanding  human health, and disease.  Ethical issues in animal research, genetic manipulation, and disease modeling are highlighted.

Prerequisite: LMP300Y1/BIO260H1/HMB265H1
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP410H1:    Pathobiology of Neurodegenerative Disease
Molecular basis of neurodegenerative diseases of the central and peripheral nervous systems. Relevant neuroanatomy and molecular biology of the CNS. Current research topics in neurodegenerative diseases.

Prerequisite: (BIO240H1, BIO241H1)/BIO255Y1/(PSL300H1, PSL301H1)/PSL302Y1
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP415H1:    Forensic Pathobiology
A thematic review of the major scientific areas and research controversies in forensic medicine. The approach is mechanistic analysis and evidence-based medicine. Classical forensic medicine is critically analyzed with emphasis on experimental meth-ods to resolve controversies. We also explore how the justice system utilizes medical and scientific data.

Prerequisite: LMP300Y1
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)

LMP436H1:    Microbial Pathogenesis
Molecular mechanism involved in pathogenesis of infectious disease. Topics include recurrent themes in the establishment of infectious disease, such as adherence and spread of pathogenic bacteria as well as evasion of host defences. Emphasis is placed on genetic characterization and expression of virulence determinants and on interactions between bacterial pathogens and their hosts.

Prerequisite: BCH210H1/BCH242Y1, IMM340H1/IMM350H1
Distribution Requirement Status: This is a Science course
Breadth Requirement: Living Things and Their Environment (4)